Significant improvements in lifestyle and medical science are leading to an ever increasing elderly population in the United States and other developed nations.

Recognition that aging is not the accumulation of disease, but rather comprises fundamental biological processes that are amenable to experimental study, is the

The Handbook of Models for Human Aging is designed as the only comprehensive work available that covers the diversity of aging models currently available. For e

The costs associated with a drug's clinical trials are so significant that it has become necessary to validate both its safety and efficacy in animal models pri

Neurodegenerative diseases are the most frequent cause of dementia, representing a burden for public health systems (especially in middle and middle-high income