Calcium Homeostasis

Download or read book Calcium Homeostasis written by Gregory R. Mundy and published by Martin Dunitz. This book was released on 1990 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a straightforward account of the physiological mechanisms which regulate the concentration of calcium in the extracellular fluid, and the diseases which upset the homeostasis of calcium. In this revised and updated edition, new data concerning the mechanisms of hypercalcemia of malignancy, the calcium exchange mechanism between bone and extracellular fluid, PTH-related protein, interleukin-6 and the new generation of biospheres is presented. This volume also covers principles underlying calcium homeostasis and the roles of bone, kidney and gut, as well as major hormonal factors. Hypercalcemia of malignancy and hypercalcemia associated with osteolytic metastases and hematologic malignancies are also stressed. Throughout, the author examines causes, clinical features, differential diagnosis, and treatment. This excellent, accessible account is an outstanding reference for both practitioners and researchers.