Molecular Mechanisms of Bacterial Infection via the Gut

Molecular Mechanisms of Bacterial Infection via the Gut
Author :
Publisher : Springer Science & Business Media
Total Pages : 263
Release :
ISBN-10 : 9783642018466
ISBN-13 : 3642018467
Rating : 4/5 (66 Downloads)

Book Synopsis Molecular Mechanisms of Bacterial Infection via the Gut by : Chihiro Sasakawa

Download or read book Molecular Mechanisms of Bacterial Infection via the Gut written by Chihiro Sasakawa and published by Springer Science & Business Media. This book was released on 2009-10-08 with total page 263 pages. Available in PDF, EPUB and Kindle. Book excerpt: Our gut is colonized by numerous bacteria throughout our life, and the gut epithelium is constantly exposed to foreign microbes and dietary antigens. Thus, the gut epithelium acts as a barrier against microbial invaders and is equipped with various innate defense systems. Resident commensal and foreign invading bacteria interact intimately with the gut epithelium and can impact host cellular and innate immune responses. From the perspective of many pathogenic bacteria, the gut epithelium serves as an infectious foothold and port of entry for disseminate into deeper tissues. In some instances when the intestinal defense activity and host immune system become compromised, even commensal and opportunistic pathogenic bacteria can cross the barrier and initiate local and systematic infectious diseases. Conversely, some highly pathogenic bacteria, such as those highlighted in this book, are able to colonize or invade the intestinal epithelium despite the gut barrier function is intact. Therefore, the relationship between the defensive activity of the intestinal epithelium against microbes and the pathogenesis of infective microbes becomes the basis for maintaining a healthy life. The authors offer an overview of the current topics related to major gastric and enteric pathogens, while highlighting their highly evolved host (human)-adapted infectious processes. Clearly, an in-depth study of bacterial infectious strategies, as well as the host cellular and immune responses, presented in each chapter of this book will provide further insight into the critical roles of the host innate and adaptive immune systems and their importance in determining the severity or completely preventing infectious diseases. Furthermore, under the continuous threat of emerging and re-emerging infectious diseases, the topic of gut-bacteria molecular interactions will provide various clues and ideas for the development of new therapeutic strategies.


Molecular Mechanisms of Bacterial Infection via the Gut Related Books

Bacterial Signaling
Language: en
Pages: 513
Authors: Reinhard Krämer
Categories: Science
Type: BOOK - Published: 2009-12-09 - Publisher: John Wiley & Sons

DOWNLOAD EBOOK

Providing a comprehensive insight into cellular signaling processes in bacteria with a special focus on biotechnological implications, this is the first book to
Molecular Mechanisms of Bacterial Infection via the Gut
Language: en
Pages: 260
Authors: Chihiro Sasakawa
Categories: Medical
Type: BOOK - Published: 2009-10-09 - Publisher: Springer

DOWNLOAD EBOOK

Our gut is colonized by numerous bacteria throughout our life, and the gut epithelium is constantly exposed to foreign microbes and dietary antigens. Thus, the
Molecular Mechanisms of Bacterial Infection via the Gut
Language: en
Pages: 263
Authors: Chihiro Sasakawa
Categories: Medical
Type: BOOK - Published: 2009-10-08 - Publisher: Springer Science & Business Media

DOWNLOAD EBOOK

Our gut is colonized by numerous bacteria throughout our life, and the gut epithelium is constantly exposed to foreign microbes and dietary antigens. Thus, the
Enteric Glia
Language: en
Pages: 72
Authors: Brian D. Gulbransen
Categories: Medical
Type: BOOK - Published: 2014-07-01 - Publisher: Biota Publishing

DOWNLOAD EBOOK

The enteric nervous system (ENS) is a complex neural network embedded in the gut wall that orchestrates the reflex behaviors of the intestine. The ENS is often
Regulation of Bacterial Virulence
Language: en
Pages: 1189
Authors: Michael L. Vasil
Categories: Science
Type: BOOK - Published: 2012-12-05 - Publisher: American Society for Microbiology Press

DOWNLOAD EBOOK

A comprehensive compendium of scholarly contributions relating to bacterial virulence gene regulation. • Provides insights into global control and the switch