Pathophysiology and Management of Valvular Lesions in the Setting of LVAD Support

Download or read book Pathophysiology and Management of Valvular Lesions in the Setting of LVAD Support written by Paul C. Tang and published by Frontiers Media SA. This book was released on 2023-10-09 with total page 133 pages. Available in PDF, EPUB and Kindle. Book excerpt: Durable left ventricular assist device (LVAD) technology is advancing at a rapid pace with increasing reliability of mechanical circulatory support for progressively longer periods. With more patients living longer on their LVAD as destination therapy or until eventual heart transplantation, concomitant valvular disease will have a greater impact on outcomes and patient quality of life. While some valvular lesions exist prior to LVAD implantation, others develop de novo from continuous flow mechanical support physiology. The presence of valvular disease in the setting of LVAD support is known to reduce effective cardiac output, increase left ventricular and atrial pressure, and increase right ventricular afterload. These hemodynamic changes can in turn contribute to right heart failure and negatively impact patient outcomes.