Statistical Issues in Drug Development

Statistical Issues in Drug Development
Author :
Publisher : John Wiley & Sons
Total Pages : 523
Release :
ISBN-10 : 0470723572
ISBN-13 : 9780470723579
Rating : 4/5 (72 Downloads)

Book Synopsis Statistical Issues in Drug Development by : Stephen S. Senn

Download or read book Statistical Issues in Drug Development written by Stephen S. Senn and published by John Wiley & Sons. This book was released on 2008-02-28 with total page 523 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug development is the process of finding and producingtherapeutically useful pharmaceuticals, turning them into safe andeffective medicine, and producing reliable information regardingthe appropriate dosage and dosing intervals. With regulatoryauthorities demanding increasingly higher standards in suchdevelopments, statistics has become an intrinsic and criticalelement in the design and conduct of drug development programmes. Statistical Issues in Drug Development presents anessential and thought provoking guide to the statistical issues andcontroversies involved in drug development. This highly readable second edition has been updated toinclude: Comprehensive coverage of the design and interpretation ofclinical trials. Expanded sections on missing data, equivalence, meta-analysisand dose finding. An examination of both Bayesian and frequentist methods. A new chapter on pharmacogenomics and expanded coverage ofpharmaco-epidemiology and pharmaco-economics. Coverage of the ICH guidelines, in particular ICH E9,Statistical Principles for Clinical Trials. It is hoped that the book will stimulate dialogue betweenstatisticians and life scientists working within the pharmaceuticalindustry. The accessible and wide-ranging coverage make itessential reading for both statisticians and non-statisticiansworking in the pharmaceutical industry, regulatory bodies andmedical research institutes. There is also much to benefitundergraduate and postgraduate students whose courses include amedical statistics component.


Statistical Issues in Drug Development Related Books

Statistical Issues in Drug Development
Language: en
Pages: 523
Authors: Stephen S. Senn
Categories: Medical
Type: BOOK - Published: 2008-02-28 - Publisher: John Wiley & Sons

DOWNLOAD EBOOK

Drug development is the process of finding and producingtherapeutically useful pharmaceuticals, turning them into safe andeffective medicine, and producing reli
Innovative Methods for Rare Disease Drug Development
Language: en
Pages: 321
Authors: Shein-Chung Chow
Categories: Mathematics
Type: BOOK - Published: 2020-11-11 - Publisher: CRC Press

DOWNLOAD EBOOK

In the United States, a rare disease is defined by the Orphan Drug Act as a disorder or condition that affects fewer than 200,000 persons. For the approval of "
Statistical Issues in Drug Development
Language: en
Pages: 84
Authors: Stephen S. Senn
Categories: Medical
Type: BOOK - Published: 2021-08-23 - Publisher: John Wiley & Sons

DOWNLOAD EBOOK

Statistical Issues in Drug Development The revised third edition of Statistical Issues in Drug Development delivers an insightful treatment of the intersection
Introduction to Statistical Methods for Clinical Trials
Language: en
Pages: 465
Authors: Thomas D. Cook
Categories: Mathematics
Type: BOOK - Published: 2007-11-19 - Publisher: CRC Press

DOWNLOAD EBOOK

Clinical trials have become essential research tools for evaluating the benefits and risks of new interventions for the treatment and prevention of diseases, fr
Small Clinical Trials
Language: en
Pages: 221
Authors: Institute of Medicine
Categories: Medical
Type: BOOK - Published: 2001-01-01 - Publisher: National Academies Press

DOWNLOAD EBOOK

Clinical trials are used to elucidate the most appropriate preventive, diagnostic, or treatment options for individuals with a given medical condition. Perhaps