The Role of Biofilms in Device-Related Infections

The Role of Biofilms in Device-Related Infections
Author :
Publisher : Springer Science & Business Media
Total Pages : 276
Release :
ISBN-10 : 9783540681199
ISBN-13 : 3540681191
Rating : 4/5 (99 Downloads)

Book Synopsis The Role of Biofilms in Device-Related Infections by : Mark Shirtliff

Download or read book The Role of Biofilms in Device-Related Infections written by Mark Shirtliff and published by Springer Science & Business Media. This book was released on 2008-12-19 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: Approximately 60% of all hospital-associated infections, over one million cases per year, are due to biofilms that have formed on indwelling medical devices. Device-related biofilm infections increase hospital stays and add over one billion dollars/year to U.S. hospitalization costs. Since the use and the types of indwelling medical devices commonly used in modern healthcare are continuously expanding, especially with an aging population, the incidence of biofilm infections will also continue to rise. The central problem with microbial biofilm infections of foreign bodies is their propensity to resist clearance by the host immune system and all antimicrobial agents tested to date. In fact, compared to their free floating, planktonic counterparts, microbes within a biofilm are 50 – 500 times more resistant to antimicrobial agents. Therefore, achieving therapeutic and non-lethal dosing regimens within the human host is impossible. The end result is a conversion from an acute infection to one that is persistent, chronic, and recurrent, most often requiring device removal in order to eliminate the infection. This text will describe the major types of device-related infections, and will explain the host, pathogen, and the unique properties of their interactions in order to gain a better understanding of these recalcitrant infections.


The Role of Biofilms in Device-Related Infections Related Books

The Role of Biofilms in Device-Related Infections
Language: en
Pages: 276
Authors: Mark Shirtliff
Categories: Medical
Type: BOOK - Published: 2008-12-19 - Publisher: Springer Science & Business Media

DOWNLOAD EBOOK

Approximately 60% of all hospital-associated infections, over one million cases per year, are due to biofilms that have formed on indwelling medical devices. De
Biofilm Infections
Language: en
Pages: 0
Authors: Thomas Bjarnsholt
Categories: Science
Type: BOOK - Published: 2014-10-11 - Publisher: Springer

DOWNLOAD EBOOK

This book will cover both the evidence for biofilms in many chronic bacterial infections as well as the problems facing these infections such as diagnostics and
Microbial Biofilms in Healthcare
Language: en
Pages: 166
Authors: Karen Vickery
Categories: Medical
Type: BOOK - Published: 2020-03-16 - Publisher: MDPI

DOWNLOAD EBOOK

Biofilms are ubiquitous and their presence in industry can lead to production losses. However, nowhere do biofilms impact human health and welfare as much as th
Bacterial Biofilms
Language: en
Pages: 302
Authors: Tony Romeo
Categories: Medical
Type: BOOK - Published: 2008-02-26 - Publisher: Springer Science & Business Media

DOWNLOAD EBOOK

Throughout the biological world, bacteria thrive predominantly in surface-attached, matrix-enclosed, multicellular communities or biofilms, as opposed to isolat
Biofilms in Human Diseases: Treatment and Control
Language: en
Pages: 318
Authors: Sunil Kumar
Categories: Medical
Type: BOOK - Published: 2019-11-19 - Publisher: Springer Nature

DOWNLOAD EBOOK

This book highlights treatment strategies for bacterial biofilms in connection with a variety of human diseases. In particular, it reviews bacterial biofilm for