Cholesterol Transporters of the START Domain Protein Family in Health and Disease

Download or read book Cholesterol Transporters of the START Domain Protein Family in Health and Disease written by Barbara J. Clark and published by Springer. This book was released on 2014-07-24 with total page 197 pages. Available in PDF, EPUB and Kindle. Book excerpt: Non-vesicular intracellular cholesterol transport is an important mechanism for maintaining membrane cholesterol homeostasis. Recent reports of studies directed at soluble cholesterol transport proteins indicate that aberrant expression of the START proteins may contribute to disease states associated with disorders in cholesterol homeostasis. This is an exciting new direction in the field and the purpose of this book will be to highlight the current research directed at potential roles for the START family in diabetes, cancer and atherogenesis. This book also provides a personal and historical perspective of the discovery-to-publication journey that the authors had for their particular START domain family member. The goal will be to provide perspectives to graduate students, post-doctoral fellows and endocrinology fellows on the research discovery process.