Developmental and Fetal Origins of Differences in Monozygotic Twins

Download or read book Developmental and Fetal Origins of Differences in Monozygotic Twins written by Alexandra Matias and published by Academic Press. This book was released on 2020-05-15 with total page 387 pages. Available in PDF, EPUB and Kindle. Book excerpt: Developmental and Fetal Origins of Differences in Monozygotic Twins: From Genetics to Environmental Factors examines the major causes of discordance in monozygotic twins, from genetic, to environmental influences, including discussions on the genetic, epigenetic, fetal and environmental factors. Twin differences discussed include malformations, deformations and disruptions secondary to inequitable division of the early embryo, chromosome and single gene mosaicism, Nonrandom X chromosome inactivation, mitochondrial heteroplasmy, epigenetic variation, and variable and inequitable blood supply, among other influences. Differences in hemoglobin levels, placentation and amniotic fluid are also examined, while full color images illustrate discordant anomalies and twin differences throughout. - Examines the major causes of discordance in monozygotic twins and their relevance for future studies and clinical management - Discusses NIPT in MZ twins, twin imaging during fetal development, blood tests and forensic analysis - Features contributions from international experts in twin genetics and developmental biology