Glycosphingolipids in the Central Nervous System

Download or read book Glycosphingolipids in the Central Nervous System written by Zhongwu Guo and published by Elsevier. This book was released on 2024-03-06 with total page 455 pages. Available in PDF, EPUB and Kindle. Book excerpt: Glycosphingolipids in the Central Nervous System: Diversity in Structure, Metabolism, Distribution, and Function comprehensively covers progress made in the discovery, profiling and understanding of the metabolism, function and functional mechanism of GSLs in the CNS –as well as their synthesis, relationships with and therapeutic applications to neurodegenerative disorders, and related CNS diseases. Due to the important roles of GSLs in the CNS and various CNS-related diseases, the interest in these biomolecules is growing. GSLs are the principal glycolipids on the cell surface and an essential constituent of the cell membrane. They are widespread, but especially enriched in the central nervous system (CNS) in vertebrates. The diversity of GSL structures forges the molecular foundation for their broad spectrum of activity. - Presents a systematic review of literature and potential future developments in Glycosphingolipid research - Highlights interdisciplinary interplay between various aspects of the neuronal system and its structural and functional properties - Provides an overview, general trends, cases studies, summaries and future implications