Handbook of Pharmacokinetic/Pharmacodynamic Correlation

Download or read book Handbook of Pharmacokinetic/Pharmacodynamic Correlation written by Hartmut Derendorf and published by CRC Press. This book was released on 1995-03-23 with total page 502 pages. Available in PDF, EPUB and Kindle. Book excerpt: Combining the established disciplines of pharmacokinetics (PK), the relationship between drug concentration and time, and pharmacodynamics (PD), the relationship between drug effects and concentration, this handbook examines the relevant relationship between drug effects and time. It provides a systematic overview of how PK is linked to PD, introduces the basic concepts of PK-PD modeling and presents the underlying theory behind it, and discusses the specific aspects of PK-PD modeling for various classes of drugs.