Integrated Diagnostics and Biomarker Discovery in Endocrinology and Biomedical Sciences

Download or read book Integrated Diagnostics and Biomarker Discovery in Endocrinology and Biomedical Sciences written by Sijung Yun and published by Frontiers Media SA. This book was released on 2024-12-02 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent advancements and cost reduction in various omics technologies have provided us with a wealth of data at the molecular, cellular and organ levels. Other types of comprehensive data sets are also increasingly available at the individual, community and population levels. The integration of these different types of data are enabling multidisciplinary convergences in diagnostics and biomarker discovery in various biomedical fields to realize a more holistic, systems biology view of diseases. Such integrated approaches have also proven useful in the field of endocrinology, particularly in better understanding complex, heterogeneous diseases such as type 2 diabetes mellitus. For instance, researchers have combined genotyping data and RNA-sequencing data with glycomics and lipidomics to identify potential biomarkers in type 2 diabetes.