This book covers domains of modern clinical trial design: classical, group sequential, adaptive, and Bayesian methods applicable to and used in various phases o

"This is truly an outstanding book. [It] brings together all of the latest research in clinical trials methodology and how it can be applied to drug development

This contributed volume offers a much-needed overview of the statistical methods in early clinical drug and biomarker development. Chapters are written by exper

This book focuses on important decision points and evidence needed for making decisions at these points during the development of a new drug. It takes a holisti

Biosimilars have the potential to change the way we think about, identify, and manage health problems. They are already impacting both clinical research and pat