Molecular Connectivity in Structure-Activity Analysis

Download or read book Molecular Connectivity in Structure-Activity Analysis written by Lemont B. Kier and published by John Wiley & Sons. This book was released on 1986-04 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Describes molecular connectivity as a structure-based approach to biological quantitative structure activity (QSAR). Significant advances which have occured over the last 10 years in methodology and its signifiance are covered along with more recent advances in the area of electronic description Some examples of quantitative structure-activity relationships are presented which reveal the value of the method in biological studies. New research is presented, particularly in the areas of shape definition, aromaticity, and molecular flexibility.