Monogenic Hyperinsulinemic Hypoglycemia Disorders

Monogenic Hyperinsulinemic Hypoglycemia Disorders
Author :
Publisher : Karger Medical and Scientific Publishers
Total Pages : 206
Release :
ISBN-10 : 9783805599436
ISBN-13 : 3805599439
Rating : 4/5 (36 Downloads)

Book Synopsis Monogenic Hyperinsulinemic Hypoglycemia Disorders by : Charles A. Stanley

Download or read book Monogenic Hyperinsulinemic Hypoglycemia Disorders written by Charles A. Stanley and published by Karger Medical and Scientific Publishers. This book was released on 2012 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular mechanisms, clinical manifestations and new treatments In this volume of 'Frontiers in Diabetes' dealing with the molecular basis of monogenic disease of beta-cell insulin regulation, world-renowned experts provide in-depth descriptions of the many recent advances in genetic defects that cause hyperinsulinemic hypoglycemia. These disorders comprise the most important form of hypoglycemia in infants and children and are associated with a high risk of morbidity, including seizures and severe brain injury. The discovery of eight different genetic loci involved in congenital hyperinsulinism has led to greatly improved methods of diagnosis and treatment. New approaches to diagnosis are highlighted, such as 18F-DOPA PET scans for preoperative localization of focal hyperinsulinism, as well as potential new treatments, such as green tea polyphenols for GDH-HI and GLP- receptor antagonists for SUR1 and Kir6.2 hyperinsulinism. Practitioners, including pediatricians and specialists in endocrinology, surgery, genetics, pathology, and radiology, will find important up-to-date information for clinical diagnosis, management, and new treatments for infants and children with congenital hyperinsulinism. Researchers will discover how genetic hyperinsulinism disorders provide novel insights into the basic mechanisms regulating insulin secretion not only in diabetics, but also in healthy humans.


Monogenic Hyperinsulinemic Hypoglycemia Disorders Related Books

Monogenic Hyperinsulinemic Hypoglycemia Disorders
Language: en
Pages: 206
Authors: Charles A. Stanley
Categories: Medical
Type: BOOK - Published: 2012 - Publisher: Karger Medical and Scientific Publishers

DOWNLOAD EBOOK

Molecular mechanisms, clinical manifestations and new treatments In this volume of 'Frontiers in Diabetes' dealing with the molecular basis of monogenic disease
Monogenic Hyperinsulinemic Hypoglycemia Disorders
Language: en
Pages: 206
Authors: D.D. De Léon
Categories: Medical
Type: BOOK - Published: 2012-02-16 - Publisher: Karger Medical and Scientific Publishers

DOWNLOAD EBOOK

In this volume of 'Frontiers in Diabetes' dealing with the molecular basis of monogenic disease of beta-cell insulin regulation, world-renowned experts provide
Inherited Metabolic Disease in Adults
Language: en
Pages: 657
Authors: Carla E. M. Hollak
Categories: Medical
Type: BOOK - Published: 2016 - Publisher: Oxford University Press

DOWNLOAD EBOOK

As clinical management of inherited metabolic diseases (IMDs) has improved, more patients affected by these conditions are surviving into adulthood. This trend,
Next Generation Sequencing Based Clinical Molecular Diagnosis of Human Genetic Disorders
Language: en
Pages: 366
Authors: Lee-Jun C. Wong
Categories: Science
Type: BOOK - Published: 2017-05-15 - Publisher: Springer

DOWNLOAD EBOOK

Next Generation Sequencing technology has been applied to clinical diagnoses in the past three to five years using various approaches, including target gene pan
Pediatric Endocrinology
Language: en
Pages: 616
Authors: Sally Radovick
Categories: Medical
Type: BOOK - Published: 2013-02-20 - Publisher: Springer Science & Business Media

DOWNLOAD EBOOK

A state-of-the-art and concise guide to the clinical management of pediatric endocrine disorders, the second edition of the highly regarded Pediatric Endocrinol