Preparation, Function and Application of Postbiotics

Download or read book Preparation, Function and Application of Postbiotics written by Zhaojie Li and published by Frontiers Media SA. This book was released on 2024-10-18 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt: An increasing number of studies on probiotics have found strong evidence that bacterial viability is not essential for imparting health benefits. It has been demonstrated in many studies that inactivated bacteria, bacterial cell components (peptidoglycans, lipoteichoic acids), or probiotic-derived metabolites (vitamins, polyphenols, bacteriocin, exopolysaccharides, short-chain fatty acids) can significantly improve host health. In 2021, the International Scientific Association for Probiotics and Prebiotics (ISAPP) convened a panel of experts specializing in nutrition, microbial physiology, gastroenterology, pediatrics, food science and microbiology to propose a useful definition of “postbiotic”, which was defined as a “preparation of inanimate microorganisms and/or their components that confers a health benefit on the host.” Postbiotics have been proven to be excellent health effectors with multiple functions, including alleviating inflammatory bowel syndrome, eradicating Helicobacter pylori residing from the stomach, abrogating the negative effects of stress, anti-inflammation, anti-bacteria, alleviating asthma, anti-infection, anti-tumor, anti-allergy, and so on. In addition to these beneficial effects listed above, postbiotics have several advantages over probiotics, including higher safety, a longer shelf life, and more sites of action (e.g., gut, skin, oral cavity, urogenital tract, or nasopharynx), which will broaden their application fields.