The Modernist

Download or read book The Modernist written by Robert Klanten and published by Gestalten. This book was released on 2011 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Methods and Applications of Statistics in Clinical Trials, Volume 1: Concepts, Principles, Trials, and Designs "focuses on all the key principles, various clinical trials used and different designs that could be applied for clinical trials. This volume discusses the key statistical concepts that are essential in understanding how to design and construction of clinical trials. This volume provides detailed explanations of statistical concepts such as longitudinal data, missing data, covariates, biased-coin randomization, repeated measurements, and simple randomization, which are used in creating and analyzing the data gleaned from clinical trials. Volume 1 also presents several detailed overviews of various trial designs that can be found within the various phase I-IV trials, such as adaptive, crossover, group-randomized, multicenter, non-inferiority, non-randomized, open-labeled, preference, prevention, and superiority trials. In addition, an overview is presented of various clinical trials that are currently active, including AIDS clinical trials group (ACTG), early cancer & heart disease clinical trials, multiple risk factor intervention trial (MRFIT), and mother to child human immunodeficiency virus transmission trials.